Mycobacterium Species Related to M. leprae and M. lepromatosis from Cows with Bovine Nodular Thelitis
نویسندگان
چکیده
Bovine nodular thelitis is a granulomatous dermatitis associated with infection with acid-fast bacteria. To identify the mycobacterium responsible for this infection, we conducted phylogenetic investigations based on partial sequencing of 6 genes. These bacteria were identified as an undescribed Mycobacterium species that was phylogenetically related to M. leprae and M. lepromatosis.
منابع مشابه
Detection of the Leprosy Agent Mycobacterium lepromatosis in South America and Europe
I read with interest the recent article “Two Cases of Leprosy in Siblings Caused by Mycobacterium lepromatosis and Review of the Literature” by Sotiriou and others. I noted omission of a 2014 article that reported detection of M. lepromatosis in Brazil and Myanmar. The omission made the literature review incomplete, and more relevantly, failed to recognize wider geographic distribution of the a...
متن کاملComparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis.
Mycobacterium lepromatosis is a newly discovered leprosy-causing organism. Preliminary phylogenetic analysis of its 16S rRNA gene and a few other gene segments revealed significant divergence from Mycobacterium leprae, a well-known cause of leprosy, that justifies the status of M. lepromatosis as a new species. In this study we analyzed the sequences of 20 genes and pseudogenes (22,814 nucleoti...
متن کاملMycobacterium leprae: pathogenic agent in leprosy. Discovery of new species Mycobacterium lepromatosis. Perspectives in research and diagnosis of leprosy.
BACKGROUND M. leprae was presumed as an aetiologic agent in DLL, without specific microbiologic studios in the past. The sequencing of the genome through genetic testing led to the discovery of a new species M. lepromatosis by Han et al. in 2008. MATERIALS AND METHODS The genetic analysis of the phylogeny of bacteria, based on the analysis of the 16S rRNA coding regions and other genes (eg, r...
متن کاملInfection with Mycobacterium lepromatosis
Microbiologically speaking, the ancient scourge of leprosy has a new face. Considered a curse for millennia, the causative agent, Mycobacterium leprae, was first described by Armauer Hansen in 1874. This inaugurated the field of medical microbiology, preceding the discovery of Mycobacterium tuberculosis. But M. leprae is not cultivable, a fact that has greatly hindered many of the basic studies...
متن کاملWhat is the evidence that the putative Mycobacterium lepromatosis species causes diffuse lepromatous leprosy?
Han et al. have made a retrospective isolation of DNA from two patients with fatal Lucio's phenomenon. This DNA does have some molecular differences to M. leprae and may constitute a variant of M. leprae. However the experiments and data needed to confirm that this is a new leprosy-causing species have not yet been done. We have outlined the work that does need to be done. For the moment the as...
متن کامل